Peyote

The peyote (/peɪˈoʊti/; Lophophora williamsii /ləˈfɒfərə wɪliˈæmziaɪ/) is a small, spineless cactus which contains psychoactive alkaloids,[2] particularly mescaline.[3] Peyote is a Spanish word derived from the Nahuatl peyōtl ([ˈpejoːt͡ɬ]), meaning "caterpillar cocoon", from a root peyōni, "to glisten".[4][5][6] Peyote is native to Mexico and southwestern Texas. It is found primarily in the Sierra Madre Occidental, the Chihuahuan Desert and in the states of Nayarit, Coahuila, Nuevo León, Tamaulipas, and San Luis Potosí among scrub. It flowers from March to May, and sometimes as late as September. The flowers are pink, with thigmotactic anthers (like Opuntia).
Known for its psychoactive properties when ingested, peyote has at least 5,500 years of entheogenic and medicinal use by indigenous North Americans.